Yah.
Back in hte day if you did not have load on the 3.3/5v rails, it could cause problems. Dunno if that is still the case. Which was why I recomended running sata drives off the second PSU (the real 5 wire sata power not hte molex adapted kind) A lot of PSU comapnies run only 4 wires to the sata ports, these are "adpaters" not really sata power plug. Must have the 5th line for 3.3v. (Without it I do not think you can hot swap the sata drives.)
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