I was told this a long time ago about ramdisk and pi
...RamDisk doesn't work well for Spi because in order to use it, you trade off from actual ram size for the ramdisk size... in 32bit the are so many adresses - blah blah blah (how memory works and irql talk). On 64bit you might be able to use ramdisk with some positive results, but the same basic memory rules apply..
I paraphrased it just a tad...